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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
SNAP25
All Species:
20
Human Site:
S154
Identified Species:
33.85
UniProt:
P60880
Number Species:
13
Phosphosite Substitution
Charge Score:
0
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
P60880
NP_003072.2
206
23315
S154
D
E
N
L
E
Q
V
S
G
I
I
G
N
L
R
Chimpanzee
Pan troglodytes
Rhesus Macaque
Macaca mulatta
XP_001105155
211
23235
G160
E
E
N
L
T
Q
V
G
S
I
L
G
N
L
K
Dog
Lupus familis
XP_859386
207
23459
S155
D
E
N
L
E
Q
V
S
G
I
I
G
N
L
R
Cat
Felis silvestris
Mouse
Mus musculus
O09044
210
23242
G159
E
E
N
L
T
Q
V
G
S
I
L
G
N
L
K
Rat
Rattus norvegicus
P60881
206
23297
S154
D
E
N
L
E
Q
V
S
G
I
I
G
N
L
R
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001507841
243
26184
G151
E
E
N
L
V
Q
V
G
S
V
L
G
N
L
R
Chicken
Gallus gallus
XP_421159
209
23585
G158
D
E
N
L
T
Q
V
G
N
I
L
G
N
L
K
Frog
Xenopus laevis
NP_001080510
206
23168
G154
D
E
N
L
E
Q
V
G
G
I
I
G
N
L
R
Zebra Danio
Brachydanio rerio
Q5TZ66
204
22839
G152
D
E
N
L
E
Q
V
G
G
I
I
G
N
L
R
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
P36975
212
23667
N162
E
E
N
M
G
Q
V
N
T
M
I
G
N
L
R
Honey Bee
Apis mellifera
XP_394588
213
23546
N163
E
E
N
M
G
Q
V
N
T
M
I
G
N
L
R
Nematode Worm
Caenorhab. elegans
P83351
277
31097
S193
D
E
N
L
D
M
M
S
A
N
L
R
N
L
Q
Sea Urchin
Strong. purpuratus
NP_999754
212
23995
S160
D
E
N
L
T
Q
V
S
G
I
V
G
N
L
R
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Q9LMG8
263
29057
S212
D
D
G
L
S
D
L
S
D
I
L
G
D
L
K
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
N.A.
60.6
94.1
N.A.
61.4
100
N.A.
57.6
59.3
95.1
93.1
N.A.
60.3
60.5
22.3
60.3
Protein Similarity:
100
N.A.
76.3
97
N.A.
77.6
100
N.A.
67.9
76.5
97
96.1
N.A.
75
74.1
38.6
74.5
P-Site Identity:
100
N.A.
60
100
N.A.
60
100
N.A.
60
66.6
93.3
93.3
N.A.
60
60
46.6
86.6
P-Site Similarity:
100
N.A.
80
100
N.A.
80
100
N.A.
80
80
93.3
93.3
N.A.
86.6
86.6
73.3
93.3
Percent
Protein Identity:
N.A.
N.A.
N.A.
23.1
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
42.5
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
40
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
73.3
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
0
0
0
0
0
0
0
8
0
0
0
0
0
0
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
65
8
0
0
8
8
0
0
8
0
0
0
8
0
0
% D
% Glu:
36
93
0
0
36
0
0
0
0
0
0
0
0
0
0
% E
% Phe:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% F
% Gly:
0
0
8
0
15
0
0
43
43
0
0
93
0
0
0
% G
% His:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% H
% Ile:
0
0
0
0
0
0
0
0
0
72
50
0
0
0
0
% I
% Lys:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
29
% K
% Leu:
0
0
0
86
0
0
8
0
0
0
43
0
0
100
0
% L
% Met:
0
0
0
15
0
8
8
0
0
15
0
0
0
0
0
% M
% Asn:
0
0
93
0
0
0
0
15
8
8
0
0
93
0
0
% N
% Pro:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% P
% Gln:
0
0
0
0
0
86
0
0
0
0
0
0
0
0
8
% Q
% Arg:
0
0
0
0
0
0
0
0
0
0
0
8
0
0
65
% R
% Ser:
0
0
0
0
8
0
0
43
22
0
0
0
0
0
0
% S
% Thr:
0
0
0
0
29
0
0
0
15
0
0
0
0
0
0
% T
% Val:
0
0
0
0
8
0
86
0
0
8
8
0
0
0
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _